Name | 3-O-Ethyl-L-ascorbic acid |
Synonyms | VC ethyl ether Ethyl ascorbic acid ETHYL ASCORBIC ACID vitamin C ethyl ether 3-O-ETHYLASCORBICACID 3-O-Ethyl Ascorbyl Ether 3-O-Ethyl-L-ascorbic acid 3-O-Ethyl vitamin C ester 3-O-Ethyl-L-ascorbic Acid 3-o-ethyl-l-ascorbic acid (R)-5-((S)-1,2-dihydroxyethyl)-4-ethoxy-3-hydroxyfuran-2(5H)-one (5R)-5-[(1S)-1,2-Dihydroxyethyl]-4-ethoxy-3-hydroxy-5H-furan-2-one (5r)-5-[(1s)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-5h-furan-2-one (5R,1'S)-5-(1,2-Dihydroxy-ethyl)-4-ethoxy-3-hydroxy-5H-furan-2-one (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxyfuran-2(5H)-one (non-preferred name) |
CAS | 86404-04-8 |
EINECS | 617-849-3 |
InChI | InChI=1/C8H12O6/c1-2-13-7-5(11)8(12)14-6(7)4(10)3-9/h4,6,9-11H,2-3H2,1H3/t4-,6+/m0/s1 |
Molecular Formula | C8H12O6 |
Molar Mass | 204.18 |
Density | 1.46g/cm3 |
Melting Point | 112.0 to 116.0 °C |
Boling Point | 551.5°C at 760 mmHg |
Flash Point | 228.5°C |
Vapor Presure | 1.84E-14mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | 1.555 |
MDL | MFCD09261382 |
Use | Vitamin C ethyl ether (VC ethyl ether) is a kind of lipophilic and hydrophilic Amphoteric vitamin C derivatives, not only retains the oxidation-reduction effect of vitamin C and is very stable, is not discolored vitamin C derivatives, and it is a lipophilic hydrophilic amphoteric substance, which not only makes it extremely convenient to use in the formula, but also makes it easy to penetrate the stratum corneum into the dermis, after entering the skin, it is easily decomposed by biological enzymes to play the role of vitamin C, thereby improving its bioavailability. |
[application] whitening and freckle removal products, anti-aging products, aqua, gel, essence, lotion, skin cream, etc.
[Recommended Dosage] 0.1-2.0%, suitable for whitening and freckle removal products, wrinkle removal and anti-aging products.
[Operation Suggestions] It is best to use it under PH3.0-6.0 conditions, with the best whitening and freckle removal effect.
3-O-ethylascorbic acid ether is an antioxidant that can be prepared by the following steps:
1. Preparation materials: Vitamin C (ascorbic acid) and ethanol are required.
2. Add vitamin C to a reaction flask under dry and anhydrous conditions.
3. Add ethanol to the reaction bottle and stir to mix. Maintain the temperature of the reaction within an appropriate range.
During the reaction, it was observed that vitamin C began to dissolve and react with ethanol.
5. Continue stirring the reaction for a period of time to allow the reaction to proceed fully.
After the reaction is complete, remove the remaining ethanol from the solvent by distillation or concentration.
7. The crystalline products can be purified through recrystallization and washed and dried with appropriate solvents.
In this way, 3-O-ethyl ascorbic acid ether can be obtained. It should be noted that during the preparation process, attention should be paid to operational safety, appropriate reaction conditions should be maintained, and necessary purification and testing should be carried out to ensure high purity products are obtained.
melting point | 112.0 to 116.0 °C |
boiling point | 551.5±50.0 °C(Predicted) |
density | 1.46±0.1 g/cm3(Predicted) |
storage conditions | Sealed in dry,2-8°C |
acidity coefficient (pKa) | 8.89±0.40(Predicted) |
InChIKey | ZGSCRDSBTNQPMS-UJURSFKZSA-N |